產品名稱：Rabbit Anti-Zyxin  antibody

Rabbit Anti-Zyxin  

別名：ESP2; HED2; ZYX; Zyxin2.    

來源：Rabbit

克隆類型：Polyclonal

濃度：1mg/ml

亞型：IgG

應用： WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200,IF=1:50-1:200,IP=1:20-1:50

反應: (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)

理論分子量：61kDa

免疫原：KLH conjugated synthetic peptide derived from human Zyxin

保存：-20℃
保質期：1年

產品名稱：Anti-Zyxin antibody

Mouse Anti-Zyxin 

別名：ESP2; HED2; ZYX; Zyxin2. 

來源：Mouse

克隆類型：Monoclonal

濃度：1mg/ml

亞型：IgG

應用： WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200,IF=1:50-1:200,IP=1:20-1:50

反應: Human

理論分子量：61kDa

免疫原：KLH conjugated synthetic peptide derived from human Zyxin

保存：-20℃
保質期：1年

 Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

Recombinant human Zyxin   

ESP2; HED2; ZYX; Zyxin2. 

濃度：1mg/ ml

來源：Recombinant Human

純度：≥90% SDS-PAGE

表達系統：Mammalian

標簽：His tag N-Terminus

蛋白長度：Full length protein

預測分子量：61 kDa

內毒素水平：<1.000 Eu/µg

純化方法：HPLC

應用：SDS-PAGE，Western blot，ELISA

Biological activity,immunology research

保存：-20℃

保質期：1年

Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.